Oncology Organoid Pancreas
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Pancreatic cancer organoid-screening captures personalized sensitivity and chemoresistance suppression upon cytochrome P450 3A5-targeted inhibition

Meritxell B. Cutrona,1,4,*Jing Wu,1Ka Yang,2Junmin Peng,2,3and Taosheng Chen
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1Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, TN 38105-3678, USA2Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105-3678, USA3Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, TN 38105-3678, USA
4 Lead Contact*Correspondence:meritxell.baocutrona@stjude.org(M.B.C.),taosheng.chen@stjude.org(T.C.)https://doi.org/10.1016/j.isci.2024.110289iScience27, 110289, July 19, 2024ª2024 The Author(s). Published by Elsevier Inc.This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).1llOPENACCESS
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