Beyond the mouse: organoids, spheroids, and organs-on-chips as the (inevitable) future of malaria research?

This narrative review examines the current landscape of murine malaria models, their major contributions and translational limitations, and the growing importance of micro physiological systems, with their limitations, in next-generation malaria research.
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Dormoi J, Amalvict R, Pradines B. Beyond the mouse: organoids, spheroids, and organs-on-chips as the (inevitable) future of malaria research? Malar J. 2026 Jun 8. doi: 10.1186/s12936-026-05980-3. Epub ahead of print. PMID: 42260590.

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