Automated and scalable expansion of human liver organoids for translational applications

'Here, we present a novel strategy using an automated bioreactor platform that enables large-scale expansion of human liver organoids'.
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ten Dam, M.J., Jno Baptiste - Sam, JE.S., Schwanen, R.S. et al. Automated and scalable expansion of human liver organoids for translational applications. J Transl Med 24, 754 (2026). https://doi.org/10.1186/s12967-026-08169-z

Authors and Affiliations

  1. Department Biomedical Engineering, Eindhoven Technical University, Eindhoven, The Netherlands

    Marjolein J.M. ten Dam

  2. Scinus Cell Expansion Netherlands B.V., Zeist, The Netherlands

    Juda-El S. Jno Baptiste - Sam & Ruud Das

  3. Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands

    Rachelle S. Schwanen, Lisa van Uden & Bart Spee

  4. Department of Surgery, Erasmus MC Transplant Institute, Erasmus University Medical Center, Rotterdam, The Netherlands

    Monique M.A. Verstegen & Luc J.W. van der Laan

  5. Department of Metabolic Diseases, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

    Sabine A. Fuchs