Upcoming event highlight: Modelling aging in microphysiological systems Brussels, 9th June 2025 .

A pioneering format for addressing and discussing advancements and issues related to modelling aging mechanisms in microphysiological systems and organoids.
Upcoming event highlight: Modelling aging in microphysiological systems  Brussels, 9th June 2025  .
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AIMS 2025 will also coordinate the development of a position paper on the challenges and potential frameworks for modeling aging in microphysiological systems.

Register here

9:00-9:15 Welcome

9:15-11.00 Modelling aging in MPS

  • Andreas Stahl (Berkley): Aging in human microphysiological systems closely recreates the in vivo process with insights on rejuvenation
  • Elena Vatrano(Biomimx): Screening the efficacy of natural compounds within uKnee
  • Jang Young(Emory): Engineering 3D Microphysiological Systems to Rejuvenate Aging Skeletal Muscle
  • Aleksandra Aizenshtadt (Oslo): Liver organoids as an in vitro model in aging research
  • Hannes Campo(Northwestern): An engineered ovarian somatic organoid model preserves cellular heterogeneity and reveals cellular contributions to ovarian aging
  • Anthony Molina (UCSD):Human Cell Models of Aging and Mitochondrial Bioenergetic Decline

11:00-11:15 break

  • 11:15-12:45 Hallmarks of aging
  • Lynne Cox (Oxford): Hallmarks of aging
  • Georgina Ellison (London): tentative stem cells and regeneration
  • Elizabeth Laird(Liverpool): Considerations for modelling extracellular matrix ageing in MPS and organoids.

Lunch/poster

13:45-15:30 Modelling aging

  • George Truskey (Duke): Modeling aging using vascular microphysiological systems
  • Laura DeRooji (Vienna): Deciphering the heterogeneity of human endothelial cell aging: Integrating single-cell transcriptomics with in vitro  modelling
  • Mikolaj Ogrodnik (Vienna): Modelling of Skin Cellular Senescence Ex Vivo and in Organ Equivalents
  • Emre Kapucu (Tampere): Modeling Age-Related Neurodegenerative Diseases in Microphysiological Systems

15:30-15:45 break

15:45-16:45 Modelling hallmarks of aging

  • Simon Jones (Birmingham): Modelling of Skin Cellular Senescence Ex Vivo and in Organ Equivalents

Round table

17:00 – 18:00 Position paper

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