Upcoming event highlight: Modelling aging in microphysiological systems Brussels, 9th June 2025 .
A pioneering format for addressing and discussing advancements and issues related to modelling aging mechanisms in microphysiological systems and organoids.

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AIMS 2025 will also coordinate the development of a position paper on the challenges and potential frameworks for modeling aging in microphysiological systems.
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9:00-9:15 Welcome
9:15-11.00 Modelling aging in MPS
- Andreas Stahl (Berkley): Aging in human microphysiological systems closely recreates the in vivo process with insights on rejuvenation
- Elena Vatrano(Biomimx): Screening the efficacy of natural compounds within uKnee
- Jang Young(Emory): Engineering 3D Microphysiological Systems to Rejuvenate Aging Skeletal Muscle
- Aleksandra Aizenshtadt (Oslo): Liver organoids as an in vitro model in aging research
- Hannes Campo(Northwestern): An engineered ovarian somatic organoid model preserves cellular heterogeneity and reveals cellular contributions to ovarian aging
- Anthony Molina (UCSD):Human Cell Models of Aging and Mitochondrial Bioenergetic Decline
11:00-11:15 break
- 11:15-12:45 Hallmarks of aging
- Lynne Cox (Oxford): Hallmarks of aging
- Georgina Ellison (London): tentative stem cells and regeneration
- Elizabeth Laird(Liverpool): Considerations for modelling extracellular matrix ageing in MPS and organoids.
Lunch/poster
13:45-15:30 Modelling aging
- George Truskey (Duke): Modeling aging using vascular microphysiological systems
- Laura DeRooji (Vienna): Deciphering the heterogeneity of human endothelial cell aging: Integrating single-cell transcriptomics with in vitro modelling
- Mikolaj Ogrodnik (Vienna): Modelling of Skin Cellular Senescence Ex Vivo and in Organ Equivalents
- Emre Kapucu (Tampere): Modeling Age-Related Neurodegenerative Diseases in Microphysiological Systems
15:30-15:45 break
15:45-16:45 Modelling hallmarks of aging
- Simon Jones (Birmingham): Modelling of Skin Cellular Senescence Ex Vivo and in Organ Equivalents
Round table
17:00 – 18:00 Position paper
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